Linear 1 3-diarylpropanoids
Apexbio Technology LLC Phloretin 60-82-2 10mM (in 1mL DMSO)
Phloretin (CAS 60-82-2) is a naturally occurring dihydrochalcone phenolic compound derived primarily from apple leaves and Manchurian apricot It functions as an inhibitor of sodium-glucose linked transporters (SGLT1 and SGLT2) proteins involved in glucose uptake and reabsorption in intestinal and renal tissues Phloretin inhibits glucose uptake via these transporters exhibiting an IC50 of approximately 49 12 M In cell-based studies it enhances lipolysis increases AMP-activated protein kinase (AMPK) phosphorylation and suppresses adipogenic transcription factors and MAPK signaling Animal research demonstrates that oral administration of Phloretin reduces blood glucose and improves lipid profiles in diabetic mouse models highlighting its utility in metabolic research
Sigma Aldrich Fine Chemicals Biosciences Phospho Akt pSer473 pan
The Phospho-Akt (pSer473) ELISA (Enzyme-Linked Immunosorbent Assay) kit is a very rapid convenient and sensitive assay kit that can monitor the activation or function of important biological pathways in cell lysates.
Cell Signaling Technology Phospho-Akt (Ser473) (736E11) Rabbit mAb 20 ul
Phospho-Akt (Ser473) (736E11) Rabbit mAb 20 ul
Medchemexpress LLC 6-(4-(1-aminocyclobutyl)phenyl)-5-phenylnicotinamide | 1357158-81-6 | >98.0% | 343.42 g/mol | C22H21N3O | 10 MG
AKT-IN-1 is a small-molecule allosteric inhibitor of the AKT kinase family used for pathway and cancer research. It inhibits AKT with an IC50 of 1.042 μM, has CAS 1357158-81-6, and is supplied as a research-grade solid with high purity for biochemical and cellular assays.
- Allosteric AKT inhibition with IC50 = 1.042 μM.
- High chemical purity for reproducible results.
- Suitable for PI3K/Akt/mTOR pathway studies and cancer research.
- Solid form enabling flexible solution preparation.
- Molecular weight 343.42 g/mol and formula C22H21N3O for accurate dosing.
- Intended for research use only.
TARGETMOL CHEMICALS INC AKT-I-1 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. AKT-I-1 is a selective and reversible inhibitor of Akt1. purity: 98%