Linear 1 3-diarylpropanoids
AdipoGen Phloretin
Chemical. CAS 60-82-2. Formula C15H14O5. MW 274.27. Phloretin is a natural dihydrochalcone, originally identified from the apple tree, and is a metabolite of phlorizin. It has numerous pharmacological effects, including anti-inflammatory, antidiabetic, anticancer, antimicrobial, hepatoprotective, neuroprotective and cytoprotective properties. Phloretin is a potent antioxidant, scavenging peroxynitrite ONOO- and/or suppressing lipid peroxidation, which contributes to the many biological properties. Phloretin has anti-aging and depigmenting effects, making it also attractive for dermatological research and application. Phloretin attacks a number of molecular targets, modulating different intracellular signaling pathways, including NF-kappaB, MAPK, Nrf2, and AMPK. It can modulate Ca2 channels, PKC, GLUTs, SGLTs and other targets. The anticancer potential is based on antiproliferative, proapoptotic, antimetastatic, and antiangiogenic activities.
AdipoGen Phloretin
Chemical. CAS 60-82-2. Formula C15H14O5. MW 274.27. Phloretin is a natural dihydrochalcone, originally identified from the apple tree, and is a metabolite of phlorizin. It has numerous pharmacological effects, including anti-inflammatory, antidiabetic, anticancer, antimicrobial, hepatoprotective, neuroprotective and cytoprotective properties. Phloretin is a potent antioxidant, scavenging peroxynitrite ONOO- and/or suppressing lipid peroxidation, which contributes to the many biological properties. Phloretin has anti-aging and depigmenting effects, making it also attractive for dermatological research and application. Phloretin attacks a number of molecular targets, modulating different intracellular signaling pathways, including NF-kappaB, MAPK, Nrf2, and AMPK. It can modulate Ca2 channels, PKC, GLUTs, SGLTs and other targets. The anticancer potential is based on antiproliferative, proapoptotic, antimetastatic, and antiangiogenic activities.
Medchemexpress LLC Phloretin | 60-82-2 | 99.92% | 274.27 | 50 G
Phloretin is a flavonoid extracted from *Malus pumila Mill.* that possesses anti-inflammatory activities. It is also a specific, competitive, and orally active inhibitor of sodium/glucose cotransporters in the intestine (SGLT1) and kidney (SGLT2). Phloretin inhibits Yeast-made GLUT1 and Human erythrocyte GLUT1 with IC50 values of 49 μM and 61 μM, respectively. It has potential for the treatment of rheumatoid arthritis (RA) and allergic airway inflammation.
- Possesses anti-inflammatory activities
- Inhibits SGLT1 and SGLT2
- Inhibits Yeast-made GLUT1 and Human erythrocyte GLUT1
- Potential for treating rheumatoid arthritis and allergic airway inflammation
TARGETMOL CHEMICALS INC 4-Hydroxychalcone 500MG
Also available in 5 g, 1 mL, 100 mg and bulk. Please contact Fisher for quotes. 4'-Hydroxychalcone (2-Benzal-4-Hydroxyacetophenone) is a chalcone metabolite with hepatoprotective activity Purity 99.86%
Indofine Chemical Naringenin-7-O-Glucos, 10 Mg
NARINGENIN-7-O-GLUCOSIDE with HPLC, Flavonoid & Coumarins, 529-55-5, 99% by HPLC, 10 mg
Medchemexpress LLC γ-Glutamyl-S-1-propenyl cysteine | 91216-96-5 | 98.5% | 290.34 | 1 MG
γ-Glutamyl-S-1-propenyl cysteine is a compound isolated from garlic. It has a molecular weight of 290.34 and a CAS number of 91216-96-5. This compound is intended for research use only.
- Isolated from garlic
- Storage at -20°C, stored under nitrogen
- In solvent storage at -80°C for 6 months; -20°C for 1 month (stored under nitrogen)
- Solubility in H2O: 130 mg/mL (need ultrasonic)
- Solubility in DMSO: 4.23 mg/mL (need ultrasonic)
- Molecular formula: C11H18N2O5S
eMolecules 110231-30-6 | Diphenyl-1-pyrenylphosphine | Medchem Express | MFCD00278755 | 386.434 | C28H19Pc1ccc(cc1)P(c1ccccc1)c1ccc2ccc3cccc4ccc1c2c34 | 50mg | 795078556
Diphenyl-1-pyrenylphosphine | Medchem Express | 110231-30-6 | MFCD00278755 | 386.434 | C28H19Pc1ccc(cc1)P(c1ccccc1)c1ccc2ccc3cccc4ccc1c2c34 | 50mg | 795078556
eMolecules 110231-30-6 | Diphenyl-1-pyrenylphosphine | Medchem Express | MFCD00278755 | 386.434 | C28H19Pc1ccc(cc1)P(c1ccccc1)c1ccc2ccc3cccc4ccc1c2c34 | 5mg | 795078558
Diphenyl-1-pyrenylphosphine | Medchem Express | 110231-30-6 | MFCD00278755 | 386.434 | C28H19Pc1ccc(cc1)P(c1ccccc1)c1ccc2ccc3cccc4ccc1c2c34 | 5mg | 795078558
eMolecules 170384-29-9 | 1-(Boc-amino)-2-propanone | Accela ChemBio (ASD) | MFCD10698678 | 173.212 | C8H15NO3 | 97.000 | CC(=O)CNC(=O)OC(C)(C)C | 1g | 444752158
1-(Boc-amino)-2-propanone | Accela ChemBio (ASD) | 170384-29-9 | MFCD10698678 | 173.212 | C8H15NO3 | 97.000 | CC(=O)CNC(=O)OC(C)(C)C | 1g | 444752158
eMolecules 778-22-3 | 2,2-DIPHENYLPROPANE | AstaTech | MFCD00008794 | 196.293 | C15H16 | 95.000 | CC(C)(c1ccccc1)c1ccccc1 | 1g | 335878684
2,2-DIPHENYLPROPANE | AstaTech | 778-22-3 | MFCD00008794 | 196.293 | C15H16 | 95.000 | CC(C)(c1ccccc1)c1ccccc1 | 1g | 335878684